Osborn’s Brain, 2nd Edition

Comprehensive, visually appealing, and easy to understand, Osborn’s Brain, second edition, by the highly esteemed Dr. Anne G. Osborn, provides a solid framework for understanding the complex subject of brain imaging when studied cover to cover. Almost completely rewritten and featuring 75% new illustrations, it combines essential anatomy with gross pathology and imaging, clearly demonstrating why and how diseases appear the way they do. The most immediate emergent diagnostic topics are followed by nonemergent pathologies, integrating the most relevant information from Dr. Osborn’s entire career of accumulated knowledge, experience, and interest in neuropathology, neurosurgery, and clinical neurosciences.

New to this Edition

    • Includes new WHO classifications of brain tumors, new entities including IgG4-related disease and CLIPPERS, new and emerging infectious diseases, and updated insights into brain trauma and brain degeneration


  • Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.

Key Features

    • Covers the “must-know” aspects of brain imaging together with spectacular pathology examples, relevant anatomy, and up-to-date techniquesin neuroradiology-perfect for radiologists, neuroradiologists, neurosurgeons, and neurologists at all levels
    • Begins with emergent topics such as trauma, nontraumatic hemorrhage, stroke, and vascular lesions, followed by infections, demyelinating and inflammatory diseases, neoplasms, toxic-metabolic-degenerative disorders, and congenital brain malformations
    • Features more than 4,000 stunning, high-resolution radiologic images and medical illustrations, all of which are annotated to describe the most clinically significant features
    • Includes Dr. Osborn’s trademark summary boxes scattered throughout for quick review of essential facts, as well as the most recent and up-to-date references available


  • Helps readers think clearly about diagnoses, types of diagnoses, and the various pathologies that can affect the brain



 1 Trauma Overview
2 Primary Effects of CNS Trauma
3 Secondary Effects and Sequelae of CNS Trauma
Nontraumatic Hemorrhage and Vascular Lesions
4 Approach to Nontraumatic Hemorrhage and Vascular Lesions
5 Spontaneous Parenchymal Hemorrhage
6 Subarachnoid Hemorrhage and Aneurysms
7 Vascular Malformations
8 Arterial Anatomy and Strokes
9 Venous Anatomy and Occlusions
10 Vasculopathy
Infection, Inflammation, and Demyelinating Diseases  
 11 Approach to Infection, Inflammation, and Demyelination
12 Congenital Infections, Acquired Pyogenic and Viral Infections
13 Tuberculosis, Fungal, Parasitic, and Other Infections
15 Demyelinating and Inflammatory Diseases
Neoplasms, Cysts, and Tumor-like Lesions  
 16 Introduction to Neoplasms, Cysts, and Tumor-like Lesions
17 Astrocytomas
18 Nonastrocytic Glial Neoplasms
19 Neuronal and Mixed Neuronal-Glial Tumors
20 Pineal and Germ Cell Tumors
21 Embryonal and Neuroblastic Tumors
22 Tumors of the Meninges
23 Cranial Nerves and Nerve Sheath Tumors
24 Lymphomas, Hemopoietic and Histiocytic Tumors
25 Sellar Neoplasms and Tumor-like Lesions
26 Miscellaneous Tumors and Tumor-like Conditions
27 Metastases and Paraneoplastic Syndromes
28 Nonneoplastic Cysts
Toxic, Metabolic, and Degenerative Disorders  
 29 Approach to Toxic, Metabolic, and Systemic Diseases
30 Toxic Encephalopathy
31 Inherited Metabolic Disorders
32 Acquired Metabolic Disorders and Systemic Diseases
33 Dementias and Brain Degenerations
34 Hydrocephalus and CSF Disorders
Congenital Malformations of the Skull and Brain
35 Embryology and Classification
36 Posterior Fossa Malformations
37 Commissural and Cortical Maldevelopment
38 Holoprosencephalies, Related Disorders, and Mimics
39 Familial Tumor Syndromes
40 Neurocutaneous Syndromes without Associated Tumors
41 Anomalies of the Skull and Meninges

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